‘This brain decay occurs already from the age of 45 – these are the signs

‘This brain decay occurs already from the age of 45 – these are the signs


In the case of frontotemporal dementia remains in the memory for a long time, but the personality changed radically. Medically, the fate of the relatively young patient will not stop. What is slowing down the disease, physical and mental activity.

Frontotemporal dementia (FTD) is a rare Form of brain decay. According to the German Alzheimer’s Association, nine percent of all dementia go back a maximum of disease on the degradation of nerve cells in the Frontal lobe (frontal lobe) and in the temporal lobes (temporal lobe). Therefore, the little-known name of the disease differs from Alzheimer’s comes:

  • To a makes frontotemporal dementia very early noticeable, often with a mid-40’s.
  • To 30% the disease is inherited, for Alzheimer’s is only one percent.
  • And, unlike Alzheimer’s, remain memory and memory intact.
  • In the case of the Affected change in personality and behavior.
  • The sick self is your desinteressiertes and senseless Occur others are not aware of.

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This dementia has not robbed them Affected her being, the memory of

The neurologist Kaitlin Casaletto has performed at the Memory and Aging Center at the University of California in San Francisco, a study for FTD, which appeared in early January in the journal “Alzheimer’s and Dementia”. The researcher wanted to find out what can help the people in the middle of a part loose or irritable, apathetic, or insensitive Person.

“It is a devastating disease, and especially bad for the families, the dramatic changes in a loved one to see,” says Casaletto. “The victims themselves hold mostly for completely healthy.”

Physical and mental activity to halve the pace of decay

The study of 105 participants with the hereditary Form of the disease showed that those who are mentally and physically active, the progression could slow down the disease significantly. Compared to the most inactive group, the cognitive abilities are only half as fast downhill.

Casaletto and her colleagues conclude that improvements in life style could help the patient the most, to delay the disease. “It was a remarkable effect,” said Casaletto. “If this were a drug, would we give it to all of our patients.”

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In the most common Form of FTD, the so-called “behavioral variant”, lose the Affected, your ability, your logical Thinking and to control their emotions. The ability to think, sitting in the frontal lobe, the emotions more in the temporal lobe.

Tactless, speechless, and eventually motionless

“The connection between the two is crucial,” says Casaletto. "If in the frontal lobe, the rational control center sits, and the temporal lobe for empathy and anger are responsible, can you imagine how uncontrolled, a person will, in the case of the these areas to degenerate.“

In other FDT-variants, the disease affects mainly areas of the frontal lobe, for the naming of objects, word-finding and pronunciation of words responsible. The consequence of difficulties in reading, Writing and Speaking are.

As the disease progresses, people have problems to concentrate, to make rational decisions and to follow a conversation. Some eat unrestrained a lot, especially Sweet, to neglect the hygiene of the body or develop forced a purchase. The muscle force drops, the movements are slower and Swallowing problems. 

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The medicine can hardly help effectively

There is no cure and treatment options are limited. Antidepressants, called selective Serotonin re-uptake inhibitor, can reduce the irritability, agitation and apathy. The life-time after diagnosis is only six to ten years.

The latest Alzheimer’s research suggests that life style factors such as adequate sleep, a healthy diet as well as physical and mental exercise can improve brain health. Kaitlin Casalettos study should investigate whether this is also true for people with FT dementia.

The subjects had at the beginning of the study, only mild symptoms in the early stages of the disease. They completed the Thinking and memory tests, MRI scans to record the state of the brain. Members should lead on the cognitive and physical activities book. After two years of the initial investigations were repeated and the recorded activities will be evaluated.

Every movement and every mental employment count

The type of physical activity of the participants was not crucial. It could be walking, Jogging, and even house and garden work. “Studies show that even walking is associated with better cognitive outcomes,” says Casaletto. “It seems that every move counts.”

A cognitively active lifestyle was defined as read, Write, attend a concert, sociability maintain, solve puzzles, or have Hobbies – everything, what mattered to the brain is challenging.

The brain is still deteriorating, but the head works

The results after two years were clear: in Spite of the progressive Degeneration of brain tissue, achieved by the persons with the highest physical and intellectual activity in the cognitive Tests twice as good results as the least-active subjects.

Now the study will be continued and extended. Participants will be equipped with Fitness-trackers, in order to better understand what type of physical activity is particularly advantageous.

The message of the study: A certain amount of control over the brain health is possible

The current intermediate result is to help to overcome the attitude of “there’s nothing We can do”. “Persons at risk should feel empowered and confident that you can gain a degree of control over your brain health,” says Richard Isaacson, Director of the Alzheimer’s Prevention Clinic at the medical faculty of Cornell University in New York.

The sooner, the better: With 4 steps, you will slow down the decay of your brain

FOCUS Online/Wochit – The sooner, the better: With 4 steps brake the decay of your brain